| Human neoplastic cells in tissue culture: two established cell lines derived from giant cell tumor and fibrosarcoma. | |
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MedLine Citation:
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PMID: 1004657 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The establishment and cultivation of two human neoplastic cell lines is described. The cell line B-5GT was derived from bone giant cell tumor and B-6FS from poorly differentiated fibrosarcoma. In comparison to the normal skin fibroblasts both cell lines have a potential for "indefinite" multiplication in vitro and they exhibit growth properties which are associated with malignant transformation. The parameters investigated included cell morphology, chromosome characteristics, terminal cell density, growth pattern, residual DNA synthesis and growth in soft agar. Both cell lines exhibited human karyotype with aneuploidy and differed in their karyotype from each other. |
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Authors:
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V Thurzo; M Popovic; J Matoska; M Blasko; M Grófová; A Lizonová; M Steno |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neoplasma Volume: 23 ISSN: 0028-2685 ISO Abbreviation: Neoplasma Publication Date: 1976 |
Date Detail:
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Created Date: 1977-02-26 Completed Date: 1977-02-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0377266 Medline TA: Neoplasma Country: CZECHOSLOVAKIA |
Other Details:
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Languages: eng Pagination: 577-87 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bone Neoplasms* Cell Division Cell Line* Cell Nucleolus / ultrastructure Cell Nucleus / ultrastructure DNA, Neoplasm / biosynthesis Fibrosarcoma* Freezing Giant Cell Tumors* Humans Karyotyping Mitochondria / ultrastructure Oncogenic Viruses Preservation, Biological |
| Chemical | |
Reg. No./Substance:
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0/DNA, Neoplasm |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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