Document Detail

Human milk oligosaccharides: prebiotics and beyond.
MedLine Citation:
PMID:  19906222     Owner:  NLM     Status:  MEDLINE    
Human milk oligosaccharides (HMO) are complex glycans that are present at very high concentrations in human milk but not in infant formula. The significant energy expended by mothers to make these complex glycans suggests they must be important. How do maternal HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary gland? How can we provide formula-fed infants with HMOs or HMO-like glycans? This article reviews current knowledge and open questions on the biosynthesis and functions of HMOs.
Lars Bode
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition reviews     Volume:  67 Suppl 2     ISSN:  1753-4887     ISO Abbreviation:  Nutr. Rev.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-12     Completed Date:  2010-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376405     Medline TA:  Nutr Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S183-91     Citation Subset:  IM    
Department of Pediatrics, University of California, San Diego School of Medicine, San Diego, California, USA.
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MeSH Terms
Gastrointestinal Tract / immunology,  microbiology
Infant Formula / chemistry
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Milk, Human / chemistry*
Oligosaccharides / biosynthesis,  physiology*
Reg. No./Substance:
0/Oligosaccharides; 0/Prebiotics

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