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Human milk fatty acids profile changes during prolonged lactation: a cross-sectional study.
MedLine Citation:
PMID:  22624434     Owner:  NLM     Status:  In-Process    
BACKGROUND: Human milk produced during prolonged lactation (> 1 year) is extraordinarily rich in fat and has a higher energy content than human milk produced during short lactation.
OBJECTIVES: To estimate the fatty acid (FA) profile of human milk and to test the hypothesis that the proportion of C12 and C14 (two dietary saturated FA known to most promote hypercholesterolemia) in human milk during prolonged lactation is similar to that in short lactation.
METHODS: We conducted a cross-sectional study of 30 mothers of term infants lactating for more than 1 year as compared with 25 mothers of full-term infants who lactated for 2-6 months. Milk was collected by manual expression in mid-breastfeeding.
RESULTS: The two groups did not differ in maternal height, weight, body mass index, diet, infant birth weight and gestational age, but mothers in the prolonged lactation group were significantly older. There was a significant correlation between lactation duration and C12 or C14. The percentage of all FA combined (except for C12 and C14) decreased significantly overtime. In contrast, C12:0 and C14:0 combined increased significantly during lactation (R2 = 10.0%, P < 0.03).
CONCLUSIONS: Women who lactated for more than 1 year had higher C12 and C14 FA percentages in their milk than women who lactated for 2-6 months.
Ronit Lubetzky; Galit Zaidenberg-Israeli; Francis B Mimouni; Shaul Dollberg; Eyal Shimoni; Yael Ungar; Dror Mandel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  14     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-05-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  7-10     Citation Subset:  IM    
Department of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
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