| Human milk composition: nutrients and bioactive factors. | |
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MedLine Citation:
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PMID: 23178060 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This article provides an overview of the composition of human milk, its variation, and its clinical relevance. The composition of human milk is the biological norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation and contribute to immune maturation, organ development, and healthy microbial colonization. Some of these molecules (eg, lactoferrin) are being investigated as novel therapeutic agents. Human milk changes in composition from colostrum to late lactation, within feeds, by gestational age, diurnally, and between mothers. Feeding infants with expressed human milk is increasing. |
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Authors:
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Olivia Ballard; Ardythe L Morrow |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Pediatric clinics of North America Volume: 60 ISSN: 1557-8240 ISO Abbreviation: Pediatr. Clin. North Am. Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2012-11-26 Completed Date: 2013-01-22 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 0401126 Medline TA: Pediatr Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 49-74 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2013 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Immunobiology, Center for Interdisciplinary Research in Human Milk and Lactation, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. Olivia.Ballard@cchmc.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Breast Milk Expression Dietary Fats / metabolism Dietary Proteins / metabolism Female Humans Infant Infant Nutritional Physiological Phenomena Infant, Newborn Intercellular Signaling Peptides and Proteins / metabolism Lactation / physiology Lactose Micronutrients / metabolism Milk Banks Milk, Human / chemistry, immunology, metabolism, physiology* Pasteurization |
| Grant Support | |
ID/Acronym/Agency:
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P01 HD 13021/HD/NICHD NIH HHS; P01 HD013021/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Dietary Proteins; 0/Intercellular Signaling Peptides and Proteins; 0/Micronutrients; 63-42-3/Lactose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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