Document Detail


Human milk composition: nutrients and bioactive factors.
MedLine Citation:
PMID:  23178060     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article provides an overview of the composition of human milk, its variation, and its clinical relevance. The composition of human milk is the biological norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation and contribute to immune maturation, organ development, and healthy microbial colonization. Some of these molecules (eg, lactoferrin) are being investigated as novel therapeutic agents. Human milk changes in composition from colostrum to late lactation, within feeds, by gestational age, diurnally, and between mothers. Feeding infants with expressed human milk is increasing.
Authors:
Olivia Ballard; Ardythe L Morrow
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Pediatric clinics of North America     Volume:  60     ISSN:  1557-8240     ISO Abbreviation:  Pediatr. Clin. North Am.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2012-11-26     Completed Date:  2013-01-22     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  0401126     Medline TA:  Pediatr Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  49-74     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Breast Milk Expression
Dietary Fats / metabolism
Dietary Proteins / metabolism
Female
Humans
Infant
Infant Nutritional Physiological Phenomena
Infant, Newborn
Intercellular Signaling Peptides and Proteins / metabolism
Lactation / physiology
Lactose
Micronutrients / metabolism
Milk Banks
Milk, Human / chemistry,  immunology,  metabolism,  physiology*
Pasteurization
Grant Support
ID/Acronym/Agency:
P01 HD 13021/HD/NICHD NIH HHS; P01 HD013021/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Dietary Fats; 0/Dietary Proteins; 0/Intercellular Signaling Peptides and Proteins; 0/Micronutrients; J2B2A4N98G/Lactose
Comments/Corrections

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