| Human lymphoblastoid interferon therapy for advanced renal cell carcinoma. | |
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MedLine Citation:
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PMID: 6506397 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antitumor activity of human lymphoblastoid interferon (HLBI) in advanced renal cell carcinoma was studied. Intramuscular injection at a dose of 3 X 10(6) IU was given daily to 18 patients, including 14 patients who had undergone nephrectomy and 4 patients who had not undergone the procedure. One patient (5.6%) showed complete remission; 2 patients (11.1%) minor remission, 8 patients (44.4%) stable disease, and 7 patients (38.9%) progression. Three responders were the patients who had had nephrectomy, and whose metastatic sites were lung. Tumor responses were observed in patients with renal cell carcinoma of clear cell type or mixed type of clear cells and granular cells. We concluded that interferon has a potential antitumor activity in selected patients with advanced renal cell carcinoma. |
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Authors:
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K Marumo; M Murai; M Hayakawa; H Tazaki |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Urology Volume: 24 ISSN: 0090-4295 ISO Abbreviation: Urology Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-01-14 Completed Date: 1985-01-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0366151 Medline TA: Urology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 567-71 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Renal Cell / radiography, secondary, therapy* Humans Injections, Intramuscular Interferon Type I / administration & dosage, adverse effects, therapeutic use* Kidney Neoplasms / therapy* Lung / radiography Lung Neoplasms / radiography, secondary, therapy Male Middle Aged Nephrectomy |
| Chemical | |
Reg. No./Substance:
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0/Interferon Type I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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