| Human immunodeficiency virus infection in North American women: experience with 200 cases and a review of the literature. | |
| | |
MedLine Citation:
|
PMID: 1921705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This study was designed to define the epidemiology and natural history of human immunodeficiency virus (HIV) infection in women in Rhode Island. Two hundred women referred to Brown University physicians from 1986 through 1990 were evaluated at 3-to-6-month intervals for 12 to 60 months. All received antiretroviral therapy and prophylaxis against opportunistic infections when indicated on the basis of CD4 lymphocyte counts. Major findings included: 1) rapid shift of dominant mode of transmission from intravenous drug sharing to heterosexual route; 2) significant gender-specific differences in clinical presentation; 3) increased frequency of cervical dysplasia in women infected via intravenous needle sharing; 4) no definite gender-specific differences in progression of HIV infection; 5) enormous societal impact of HIV infection in women. Principal conclusions are: 1) rapid change to predominantly heterosexual HIV transmission can occur in North America, with serious societal impact; 2) gender-specific clinical features can lead to earlier diagnosis of HIV infection in women; 3) HIV infection in women does not pursue an inherently more rapid course than that observed in men. |
| | |
Authors:
|
C C Carpenter; K H Mayer; M D Stein; B D Leibman; A Fisher; T C Fiore |
Related Documents
:
|
17354235 - Six-month natural history of oral versus cervical human papillomavirus infection. 1174405 - Human-to-human transmission of pseudomonas pseudomallei. 9505175 - The probability of acquiring primary toxoplasma infection in hiv-infected patients: res... 18669425 - Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal hiv transm... 19182485 - A literature review of international implementation of opioid substitution treatment in... 14596225 - Practical applications of the hiv lipodystrophy case definition. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Medicine Volume: 70 ISSN: 0025-7974 ISO Abbreviation: Medicine (Baltimore) Publication Date: 1991 Sep |
Date Detail:
|
Created Date: 1991-11-07 Completed Date: 1991-11-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 2985248R Medline TA: Medicine (Baltimore) Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 307-25 Citation Subset: AIM; IM; X |
Affiliation:
|
Brown University AIDS Program, Providence, RI 02906. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Demography Female HIV Infections / complications, epidemiology*, transmission Humans Incidence Rhode Island / epidemiology Sex Factors Sexual Behavior Social Problems Socioeconomic Factors Substance Abuse, Intravenous Uterine Cervical Dysplasia / complications |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Leiomyosarcoma of the inferior vena cava. Experience with 7 patients and literature review.
Next Document: Evolution of ribosomal RNA gene copy number on the sex chromosomes of Drosophila melanogaster.