Document Detail


Human herpesvirus-6 (HHV-6)-associated hemophagocytic syndrome.
MedLine Citation:
PMID:  10897817     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Virus-associated hemophagocytic syndrome (VAHS) is characterized by histiocytic proliferation and phagocytosis triggered by virus infections. Viruses in the herpes group, especially the Epstein-Barr virus (EBV), are well known to cause VAHS; however, the relationship between this syndrome and human herpesvirus-6 (HHV-6) infection has rarely been reported. In this study, we describe a 23-month-old girl who exhibited typical manifestations of VAHS associated with HHV-6 infection. To the best of our knowledge, this case is the fifth reported case in the English literature.
Authors:
M Takagi; A Unno; T Maruyama; K Kaneko; K Obinata
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  13     ISSN:  0888-0018     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:    1996 Sep-Oct
Date Detail:
Created Date:  2000-08-25     Completed Date:  2000-08-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  451-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Koshigaya Municipal Hospital, Saitama, Japan. mtakagi@nch.go.jp
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Viral / blood
Blood Coagulation Disorders / etiology
DNA, Viral / blood
Exanthema / etiology
Female
Fever / etiology
Hepatomegaly / etiology
Herpesviridae Infections / blood,  complications*,  diagnosis
Herpesvirus 6, Human / immunology,  isolation & purification,  pathogenicity*
Histiocytosis, Non-Langerhans-Cell / complications,  diagnosis,  etiology*
Humans
Immunoglobulin M / blood
Infant
Pancytopenia / etiology
Skull Fractures / complications
Splenomegaly / etiology
Viremia / complications*,  diagnosis
Chemical
Reg. No./Substance:
0/Antibodies, Viral; 0/DNA, Viral; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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