| Human herpes virus-8 associated with two cases of primary-effusion lymphoma. | |
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MedLine Citation:
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PMID: 10901615 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary-effusion lymphoma (PEL) is a rare form of non-Hodgkin's lymphoma which predominantly occurs in patients with acquired immunodeficiency syndrome and is characterized by the presence of a malignant effusion in one or more of the body cavities, generally in the absence of a primary tumor mass. Recently, we encountered two cases of PEL presenting as cardiac tamponade. In both cases, a diagnosis of diffuse large B-cell lymphoma was made by examination of the pericardial fluid. Because human herpes virus-8 (HHV-8) antibodies were positive and human immunodeficiency virus antibodies were negative, HHV-8 seemed likely to be an etiologic agent for the PEL. One of the two patients (case 1) was not treated for religion reasons and died. The other (case 2) achieved complete remission after treatment using the CHOP regimen and is alive at present. The prognosis of this disease is believed to be poor, therefore more cases should be collected to establish reliable therapy for PEL. |
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Authors:
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N Niitsu; A Chizuka; K Sasaki; M Umeda |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of hematology Volume: 79 ISSN: 0939-5555 ISO Abbreviation: Ann. Hematol. Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-07-28 Completed Date: 2000-07-28 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9107334 Medline TA: Ann Hematol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 336-9 Citation Subset: IM; X |
Affiliation:
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First Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan. nniitsu@med.toho-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Female Herpesviridae Infections / complications Herpesvirus 8, Human / isolation & purification* Humans Lymphoma, B-Cell / virology* Lymphoma, Large B-Cell, Diffuse / complications, virology* Male |
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