Document Detail

Human fascioliasis in some areas in Cairo and Giza Governorates, Egypt.
MedLine Citation:
PMID:  15881005     Owner:  NLM     Status:  MEDLINE    
This study comprised 462 clinically suspected cases of fascioliasis. Stool examination revealed positive 11 cases for Fasciola eggs (2.38%). Serum samples were obtained for serodiagnosis from 133 suspected cases from Cairo governorate (G) and 149 from Giza G. Using IHAT, positive results were reported in 12.03% of suspected cases in Cairo G and 11.41% in Giza G. For ELISA 15.03% and 18.12% respectively were positive. Out of 462 clinically suspected cases, 58 patients were liable to be infected with Fasciola depending on the presence of Fasciola eggs in stool and/or a positive serological result with either IHAT (56.9%) or ELISA (81.03%) or both (48.28%). Serological examination of sera of cases shedding eggs revealed that one case was positive for ELISA, 4 cases were positive for IHAT and ELISA, whereas 5 cases were serologically negative. Serum from one case with Fasciola eggs in stool could not be obtained for serological diagnosis. Clinical picture of infected cases indicated that 82.76% were suffering from abdominal pain, 43.1% palor and digestive disturbances, and 25.86% fever. On physical examination, 46.55% revealed hepatomegaly. Eosino-philia was observed in 70.69% of the patients. Statistically, no significant difference (P. > 0.05) was observed among patients in both governorates regarding age, sex, clinical manifestations, detection of eggs in stool, hepatomegaly, and serological tests. However, eosinophilia was significantly higher (P < 0.05) in cases from Giza G.
Elmeya Safar; Ezzat Mikhail; Galila Bassiouni; Safeya El-Bassiouni; Hanan El-Kholy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Egyptian Society of Parasitology     Volume:  35     ISSN:  1110-0583     ISO Abbreviation:  J Egypt Soc Parasitol     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-05-09     Completed Date:  2005-07-21     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8102141     Medline TA:  J Egypt Soc Parasitol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  181-92     Citation Subset:  IM    
Research Institute of Ophthalmology, El-Ahram Street Giza, PO, Box, 90 Cairo, Egypt.
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MeSH Terms
Age Factors
Antibodies, Helminth / blood
Case-Control Studies
Egypt / epidemiology
Enzyme-Linked Immunosorbent Assay
Fasciola / immunology
Fascioliasis / diagnosis*,  epidemiology*,  pathology
Feces / parasitology
Hemagglutination Tests
Middle Aged
Parasite Egg Count
Sex Factors
Reg. No./Substance:
0/Antibodies, Helminth

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