Document Detail

Human exposure and health risk of alpha-, beta-, gamma- and delta-hexachlorocyclohexane (HCHs) in Tianjin, China.
MedLine Citation:
PMID:  15939453     Owner:  NLM     Status:  MEDLINE    
The dynamic exposures to HCHs of individuals born between the years 1913 and 1993 in Tianjin have been simulated by connecting a fugacity model (IV) with a multimedia exposure model. Ingestion is the most important pathway for human beings to take up HCHs, and concentrations in the human body correlate with body weight changes. Accumulations of HCHs were derived assuming that the degradation in human body behaved linearly. The health risk of exposure to HCHs was measured using cancer risk and loss of life expectancy (LLE), and LLE was modified from its original definition to incorporate a dynamic calculation that takes variances in exposure into account. Monte-Carlo simulations were run to analyze the uncertainties of the model.
Y Yang; S Tao; P K Wong; J Y Hu; M Guo; H Y Cao; R M Coveney; Q Zuo; B G Li; W X Liu; J Cao; F L Xu
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemosphere     Volume:  60     ISSN:  0045-6535     ISO Abbreviation:  Chemosphere     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-06-28     Completed Date:  2005-12-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  England    
Other Details:
Languages:  eng     Pagination:  753-61     Citation Subset:  IM    
College of Environmental Sciences, Laboratory for Earth Surface Processes, Peking University, Beijing 100871, China.
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MeSH Terms
Age Factors
Body Weight
Crops, Agricultural
Environmental Monitoring
Environmental Pollutants / analysis*
Food Contamination*
Insecticides / analysis*
Lindane / analysis*
Models, Theoretical
Monte Carlo Method
Pesticide Residues / analysis*
Risk Assessment
Reg. No./Substance:
0/Environmental Pollutants; 0/Insecticides; 0/Pesticide Residues; 58-89-9/Lindane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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