Document Detail

Human corticosteroid-binding capacities in normal, high-risk or pregnancies with an abnormal outcome.
MedLine Citation:
PMID:  3701147     Owner:  NLM     Status:  MEDLINE    
To determine whether or not the serum corticosteroid binding capacity (CBC) level is related to the outcome of pregnancy or fetal well-being, a total of 124 determinations of CBC were performed in 96 pregnant individuals, using hydrophobic resin adsorption methods. The serum CBC values were elevated with progression of gestation. On the other hand, high-risk pregnancies or those with an abnormal outcome were among the low CBC group, below the mean value (p less than 0.001), whereas normal pregnancies were more often in the high CBC group, over the mean value, in comparison with the low CBC group below the mean value (p less than 0.001), after 28 weeks of gestation. In addition, the ratios of birth weight/placental weight and maternal weight/placental weight were slightly but not statistically high in the low CBC group, in comparison with the high CBC group. Thus, various events related to placental growth might be important factors regulating the serum CBC level. While there are many determinants of corticosteroid binding globulin production and excretion, assessment of CBC levels seems to be a reliable indicator of the outcome of pregnancy, including high-risk pregnancy, in the 3rd trimester.
F Murao; A Yasuda; T Shibukawa; K Takahashi; K Sawada; K Kaneda; K Hasegawa; M Kitao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nihon Sanka Fujinka Gakkai zasshi     Volume:  38     ISSN:  0300-9165     ISO Abbreviation:  Nippon Sanka Fujinka Gakkai Zasshi     Publication Date:  1986 Apr 
Date Detail:
Created Date:  1986-06-09     Completed Date:  1986-06-09     Revised Date:  2011-07-29    
Medline Journal Info:
Nlm Unique ID:  7505749     Medline TA:  Nihon Sanka Fujinka Gakkai Zasshi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  590-4     Citation Subset:  IM    
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MeSH Terms
Fetal Distress / blood
Infant, Newborn
Infant, Small for Gestational Age
Pregnancy Complications / blood*
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Pregnancy in Diabetics / blood
Transcortin / metabolism*
Reg. No./Substance:

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