| Human correlates of provocative questions in pancreatic pathology. | |
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MedLine Citation:
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PMID: 23060061 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies of cell lines and of animal models of pancreatic cancer have raised a number of provocative questions about the nature and origins of human pancreatic cancer and have provided several leads into exciting new approaches for the treatment of this deadly cancer. In addition, clinicians with little or no contact with human pathology have challenged the way that pancreatic pathology is practiced, suggesting that "genetic signals" may be more accurate than today's multimodal approach to diagnoses. In this review, we consider 8 provocative issues in pancreas pathology, with an emphasis on "the evidence derived from man." |
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Authors:
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Oliver G McDonald; Anirban Maitra; Ralph H Hruban |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Advances in anatomic pathology Volume: 19 ISSN: 1533-4031 ISO Abbreviation: Adv Anat Pathol Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-10-12 Completed Date: 2013-03-21 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 9435676 Medline TA: Adv Anat Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 351-62 Citation Subset: IM |
Affiliation:
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Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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drug therapy,
genetics,
pathology* Animals Cell Line Disease Models, Animal Drug Resistance, Neoplasm Epithelial-Mesenchymal Transition Evidence-Based Medicine Gene Expression Regulation, Neoplastic Humans Mice Neoplasm Invasiveness Pancreas / pathology* Pancreatic Neoplasms / drug therapy, genetics, pathology* |
| Grant Support | |
ID/Acronym/Agency:
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P50CA062924/CA/NCI NIH HHS; T32 CA067751/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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