| Human chorionic gonadotropin supplementation in recurring pregnancy loss: a controlled trial. | |
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MedLine Citation:
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PMID: 7646609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To investigate the efficacy of hCG in the management of recurrent early pregnancy loss. DESIGN: A prospective, randomized, controlled trial. SETTING: Miscarriage Clinic, Women's Hospital, Liverpool, United Kingdom. SUBJECTS: Eighty-one women attending the miscarriage clinic with idiopathic recurrent pregnancy loss were randomized to receive hCG supplementation or placebo in early pregnancy. MAIN OUTCOME MEASURE: The success rate or live birth rate. RESULTS: In women with regular menstrual cycles it was found that hCG had no beneficial effect, the pregnancy success rate being 86% in both groups. However, women with oligomenorrhea had a pregnancy success rate of 40% in the placebo group but a statistically significant improvement to 86% if hCG was given. CONCLUSIONS: Human chorionic gonadotropin can be recommended for idiopathic recurrent pregnancy loss in women with oligomenorrhea. |
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Authors:
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S Quenby; R G Farquharson |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Fertility and sterility Volume: 62 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1994 Oct |
Date Detail:
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Created Date: 1994-11-01 Completed Date: 1994-11-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 708-10 Citation Subset: IM |
Affiliation:
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Miscarriage Clinic, Women's Hospital, Liverpool, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Habitual
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complications,
drug therapy* Adult Chorionic Gonadotropin / therapeutic use* Female Humans Menstrual Cycle Oligomenorrhea / complications Pregnancy Pregnancy Outcome Prospective Studies Reference Values |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin |
| Comments/Corrections | |
Comment In:
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Fertil Steril. 1995 Jul;64(1):215-6; author reply 216-7
[PMID:
7789567
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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