Document Detail


Human chorionic gonadotropin ratio of hemoperitoneum versus venous serum improves early diagnosis of ectopic pregnancy.
MedLine Citation:
PMID:  19046581     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To analyze the value of the hCG ratio of peritoneal serum versus venous serum (R(P/V)) for early diagnosis and prognostic evaluation of ectopic pregnancy (EP). DESIGN: Retrospective clinical study. SETTING: University hospital. PATIENT(S): One hundred three women with hemoperitoneum and positive urine hCG tests underwent laparoscopy or laparotomy. INTERVENTION(S): Venous serum and peritoneal serum samples were obtained; ultrasound was performed in all the patients; dilatation and curettage was used in 28 patients. MAIN OUTCOME MEASURE(S): Quantitative hCG and R(P/V). RESULT(S): The R(P/V) in EP (5.55 +/- 4.32) is apparently greater than that in hemoperitoneum with intrauterine pregnancy (hIUP; 0.61 +/- 0.18). The median R(P/V) is 4.07 in the EP group versus 0.60 in the hIUP group, with a suggested threshold value of 1.0 for their differential diagnosis. Moreover, the R(P/V) of EP shows the dominant difference between the patients with active bleeding (8.03 +/- 3.29, n = 24) and the patients without active bleeding (4.59 +/- 3.88, n = 16) when the hCG level of venous serum is more than 1500 U/L. CONCLUSION(S): R(P/V) could instantly diagnose ectopic pregnancy and differentiate it from hIUP.
Authors:
YuDong Wang; Hong Zhao; YinCheng Teng; LiHua Lu; JianQian Tong
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-30
Journal Detail:
Title:  Fertility and sterility     Volume:  93     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-03-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  702-5     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Chorionic Gonadotropin / blood*
Diagnosis, Differential
Early Diagnosis
Female
Hemoperitoneum / diagnosis*,  metabolism*
Humans
Pregnancy
Pregnancy, Ectopic / blood*,  diagnosis*
Prognosis
ROC Curve
Retrospective Studies
Sensitivity and Specificity
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

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