Document Detail


Human chorionic gonadotropin in the ectopic gestation.
MedLine Citation:
PMID:  2581825     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ectopic pregnancy is a relatively common condition in the south African black patients. The beta-specific subunit radioimmunoassay for human chorionic gonadotrophin (HCG) was utilized in procuring information in our series of 30 patients. Levels of the hormone were significantly lower when compared to normal gestation of similar duration, never exceeding 2000 mIU/ml. The clearance rate of HCG following normal vaginal delivery was about 24 h and less variable than that of ectopic gestation. The half-life clearance rate of HCG in the ectopics could be divided into three phases, suggestive of HCG compartmentalization. The possible buffering effect of this hormone in the maintenance of the receptor-saturated pregnancy is discussed. The possibility that the HCG produced by the normal pregnancy is dissimilar to that of ectopic is speculated upon.
Authors:
A Golan; A L Van der Walt; S Wexler; H Kort
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  23     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-07-18     Completed Date:  1985-07-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chorionic Gonadotropin / blood*,  metabolism
Chorionic Gonadotropin, beta Subunit, Human
Female
Half-Life
Humans
Peptide Fragments / blood*,  metabolism
Pregnancy
Pregnancy, Ectopic / blood*
Radioimmunoassay
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments

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