Document Detail


Human calf microvascular compliance measured by near-infrared spectroscopy.
MedLine Citation:
PMID:  10658000     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study is to develop a new method for the measurement in humans of the compliance of the microvascular superficial venous system of the lower limb by near-infrared spectroscopy (NIRS). This method is complementary to strain-gauge plethysmography, which does not allow compliance between deep and superficial venous or between venous and arterial compartments to be distinguished. In practice, hydrostatic pressure (P) changes were induced in a calf region of interest by head-up tilt of the subject from alpha = -10 to 75 degrees. For P < or = 24 mmHg, the measured compliance [0.086 +/- 0.005 (SD) ml. l(-1). mmHg(-1)] based on NIRS data of total, deoxygenated, and oxygenated hemoglobin, reflects essentially that of the superficial venous system. For P > or = 24 mmHg, no distinction can be made between arterial and venous volumes changes. However, by following the changes in oxy- and deoxyhemoglobin in the P range -16 to 100 mmHg, it appears to be possible to assess the characteristics of the vasomotor response of the arteriolar system.
Authors:
T Binzoni; V Quaresima; M Ferrari; E Hiltbrand; P Cerretelli
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  88     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-03-03     Completed Date:  2000-03-03     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  369-72     Citation Subset:  IM; S    
Affiliation:
Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland. Tiziano.Binzoni@medecine.unige.ch
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Pressure / physiology
Blood Vessels / physiology*
Compliance
Female
Hemoglobins / metabolism
Humans
Leg / blood supply*
Male
Middle Aged
Muscle, Skeletal / blood supply
Oxyhemoglobins / metabolism
Posture / physiology
Spectroscopy, Near-Infrared / methods*
Supine Position
Tilt-Table Test
Vasomotor System / physiology
Chemical
Reg. No./Substance:
0/Hemoglobins; 0/Oxyhemoglobins; 9008-02-0/deoxyhemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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