Document Detail


Human beta-globin gene HpaI polymorphism in the non-white Cuban population.
MedLine Citation:
PMID:  3154108     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The frequency of the association between the beta A, beta S and the beta C genes with the 13.0 kb HpaI restriction fragment has been determined in 72 non-white individuals with different hemoglobin phenotypes giving a value of 0.00 for the beta A gene, 0.52 for the beta S gene and 1.00 for the beta C gene. These data indicate that this association in the Cuban non-white population is similar to that reported for the American Blacks living in the U.S.A. East Coast and for the French West Indies.
Authors:
G Martinez; R Ferreira; B Colombo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gene geography : a computerized bulletin on human gene frequencies     Volume:  1     ISSN:  0394-249X     ISO Abbreviation:  Gene Geogr     Publication Date:  1987 Apr 
Date Detail:
Created Date:  1991-03-18     Completed Date:  1991-03-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9100053     Medline TA:  Gene Geogr     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  15-8     Citation Subset:  IM    
Affiliation:
Instituto de Hematología e Immunología, La Habana, Cuba.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Africa / ethnology
Anemia, Sickle Cell / genetics
Child
Cuba
Deoxyribonucleases, Type II Site-Specific*
European Continental Ancestry Group / genetics
Female
Gene Frequency*
Globins / genetics*
Humans
Male
Polymorphism, Genetic*
Chemical
Reg. No./Substance:
9004-22-2/Globins; EC 3.1.21.-/endodeoxyribonuclease HpaI; EC 3.1.21.4/Deoxyribonucleases, Type II Site-Specific

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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