Document Detail

Human amnion metabolism. I. In vitro maintenance.
MedLine Citation:
PMID:  836644     Owner:  NLM     Status:  MEDLINE    
The energy stores of human term amnion include glycogen (2.2 +/- 0.3 mumoles of glucose per gram, mean +/- S.E.) and ATP (0.13 +/- 0.2 MM.). Histologic structure and biochemical functions were preserved during incubations of amnion for 120 minutes at 37 degrees C. in a defined medium simulating amniotic fluid; glycogen concentrations were maintained at control values, and the concentration of ATP usually remained at 85 to 100 per cent of control values. Glucose utilization during the first 60 minutes of incubation was linear at a rate of 70.0 +/- 3.0 nmoles per minute per gram of tissue. It is concluded that amnion is a highly metabolically active tissue that can be maintained in a viable state in a suitable medium.
A L Schwartz; C S Forster; P A Smith; G C Liggins
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  127     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-04-01     Completed Date:  1977-04-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  470-4     Citation Subset:  AIM; IM    
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MeSH Terms
Adenosine Triphosphate / metabolism
Amnion / metabolism*,  physiology,  ultrastructure
Amniotic Fluid
Energy Metabolism
Glucose / metabolism
Glycogen / metabolism
Reg. No./Substance:
50-99-7/Glucose; 56-65-5/Adenosine Triphosphate; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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