Document Detail

Human alveolar deposition of 4 micron teflon particles.
MedLine Citation:
PMID:  686844     Owner:  NLM     Status:  MEDLINE    
On two occasions ten healthy men inhaled with maximally deep inhalations at 0.5 1/sec a test aerosol of 4 micron teflon particles tagged with 111In. Radioactivity in the lungs was measured a few min, 24 hr, and 2, 3, and 4 days after inhalation. Retention decreased greatly between the measurements performed a few min and 24 hr after inhalation, but was similar in measurements 1 to 4 days after inhalation. Among individuals, retention varied considerably 1 to 4 days after inhalation (by a factor of 2), but the retention in each individual subject was uniform. Measuring the retention of a radioactively tagged test aerosol 1 day after inhalation, and regarding this retention as alveolar deposition, might be of value in preventive measures against certain toxic dusts.
P Camner; K Philipson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of environmental health     Volume:  33     ISSN:  0003-9896     ISO Abbreviation:  Arch. Environ. Health     Publication Date:    1978 Jul-Aug
Date Detail:
Created Date:  1978-10-25     Completed Date:  1978-10-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0212627     Medline TA:  Arch Environ Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  181-5     Citation Subset:  AIM; IM    
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MeSH Terms
Indium / diagnostic use
Polytetrafluoroethylene / diagnostic use*
Pulmonary Alveoli / physiology*
Radioisotopes / diagnostic use
Time Factors
Reg. No./Substance:
0/Aerosols; 0/Radioisotopes; 7440-74-6/Indium; 9002-84-0/Polytetrafluoroethylene

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