| Human Herpesvirus 8 Infections and AIDS-Associated Kaposi Sarcoma in Zaria, Northern Nigeria. | |
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MedLine Citation:
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PMID: 21368014 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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METHODS: A total of 20 (11 males and 9 females) histologically confirmed adults with AIDS-KS were recruited consecutively in 2007. The clinical types of lesions, associated diseases, and the AIDS clinical trial group staging of AIDS-KS were noted. Anti-lytic HHV8 antibodies were determined by enzyme-linked immunosorbent assay (ELISA). RESULTS: Kaposi sarcoma skin lesions were diverse but mostly nodules (19 cases) and papules (16). Majority (18 cases) had poor risk AIDS-KS, with 10 (50%) patients having concomitant opportunistic infections and 3 (15%) patients having generalized skin lesions. Females had a more severe disease. Seventeen patients (85%) were HHV8-seropositive. CONCLUSION: AIDS-KS is associated with high HHV8 infection and presents with a variety of skin manifestations that are often aggressive, advanced, and worse in females. |
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Authors:
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Dimie Ogoina; Geoffrey C Onyemelukwe; Bolanle O P Musa; Aliyu Babadoko |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) Volume: 10 ISSN: 1545-1097 ISO Abbreviation: J Int Assoc Physicians AIDS Care (Chic) Publication Date: 2011 Jan-Feb |
Date Detail:
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Created Date: 2011-03-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101185740 Medline TA: J Int Assoc Physicians AIDS Care (Chic) Country: United States |
Other Details:
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Languages: eng Pagination: 43-8 Citation Subset: IM |
Affiliation:
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Immunology unit, Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria, dimostic@yahoo.co.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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