Document Detail


Human African trypanosomiasis: a review of non-endemic cases in the past 20 years.
MedLine Citation:
PMID:  21683638     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Human African trypanosomiasis (HAT) is caused by sub-species of the parasitic protozoan Trypanosoma brucei and is transmitted by tsetse flies, both of which are endemic only to sub-Saharan Africa. Several cases have been reported in non-endemic areas, such as North America and Europe, due to travelers, ex-patriots or military personnel returning from abroad or due to immigrants from endemic areas. In this paper, non-endemic cases reported over the past 20 years are reviewed; a total of 68 cases are reported, 19 cases of Trypanosoma brucei gambiense HAT and 49 cases of Trypanosoma brucei rhodesiense HAT. Patients ranged in age from 19 months to 72 years and all but two patients survived. Physicians in non-endemic areas should be aware of the signs and symptoms of this disease, as well as methods of diagnosis and treatment, especially as travel to HAT endemic areas increases. We recommend extension of the current surveillance systems such as TropNetEurop and maintaining and promotion of existing reference centers of diagnostics and expertise. Important contact information is also included, should physicians require assistance in diagnosing or treating HAT.
Authors:
Stephanie J Migchelsen; Philippe Büscher; Andy I M Hoepelman; Henk D F H Schallig; Emily R Adams
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-15
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  -     ISSN:  1878-3511     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Royal Tropical Institute - Biomedical Research, Parasitology, Meibergdreef 39, 1105 AZ Amsterdam, the Netherlands; Department of Internal Medicine and Infectious Disease, University Medical Centre, Universiteit Utrecht, Utrecht, the Netherlands.
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