Document Detail

Human African trypanosomiasis: MRI.
MedLine Citation:
PMID:  9351106     Owner:  NLM     Status:  MEDLINE    
We report a case of human African trypanosomiasis caused by Trypanosoma brucei rhodesiense. After the febrile period of parasite dissemination, the patient had meningeal involvement but normal CT. MRI showed the appearances of meningitis. After two periods of arsenical treatment, a severe encephalopathy occurred suggesting post-therapeutic reactive encephalitis (PTRE). Nevertheless, T2-weighted MRI showed no oedema, but focal bilateral high signal areas in the white matter. PTRE was excluded and a third course of treatment was undertaken. The lesions progressively disappeared.
P Sabbah; C Brosset; P Imbert; G Bonardel; P Jeandel; J F Briant
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuroradiology     Volume:  39     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1997-12-16     Completed Date:  1997-12-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  708-10     Citation Subset:  IM    
Department of Infectious and Tropical Diseases, HIA LAVERAN, Marseille Armées, France.
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MeSH Terms
Brain / pathology
Drug Therapy, Combination
Encephalitis / diagnosis*,  drug therapy
Magnetic Resonance Imaging*
Melarsoprol / administration & dosage
Meningitis / diagnosis*,  drug therapy
Prednisolone / administration & dosage
Tomography, X-Ray Computed
Trypanosoma brucei rhodesiense* / drug effects
Trypanosomiasis, African / diagnosis*,  drug therapy
Reg. No./Substance:
494-79-1/Melarsoprol; 50-24-8/Prednisolone

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