| Huge pedunculated angiomyofibroblastoma of the vulva. | |
| | |
MedLine Citation:
|
PMID: 20177728 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We present the case of a huge pedunculated benign mesenchymal myxoid tumor that developed on the right labia majora of a 48-year-old-woman. The excised mass weighed 4534 g and was 23 cm in diameter; the cut surface was yellowish and elastic. Microscopic examination revealed spindle and plump oval tumor cells arranged with abundant capillary vessels in an edematous stroma. Immunohistochemical staining showed that the tumor cells were positive for vimentin, desmin, estrogen receptor, and progesterone receptor, but negative for alpha-smooth muscle actin, CD34, CD45, CD68, and S-100. Based on these features, the pathological diagnosis was angiomyofibroblastoma. A pedunculated angiomyofibroblastoma is extremely rare and, to the best of our knowledge, this is the biggest such tumor in terms of size and weight reported to date. It is especially important in such a huge mass greater than 10 cm that angiomyofibroblastoma is differentiated from aggressive angiomyxoma, which is a deeply invasive and recurrent neoplasm. |
| | |
Authors:
|
Kimihiro Nagai; Koji Aadachi; Hitoaki Saito |
Related Documents
:
|
10202288 - Primary orbital leiomyoma and leiomyosarcoma. 12371598 - Distinctive pleomorphic xanthoastrocytoma-like tumor with exclusive abortive or aberran... 1466248 - A case of primary sarcoma of the pulmonary artery. 21179398 - Pi3kα inhibitors that inhibit metastasis. 12954328 - Irreversible inhibition of cd13/aminopeptidase n by the antiangiogenic agent curcumin. 20636258 - Mechanisms of tumor promotion by reactive oxygen species. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2010-02-23 |
Journal Detail:
|
Title: International journal of clinical oncology / Japan Society of Clinical Oncology Volume: 15 ISSN: 1437-7772 ISO Abbreviation: Int. J. Clin. Oncol. Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-04-12 Completed Date: 2010-07-06 Revised Date: 2011-09-13 |
Medline Journal Info:
|
Nlm Unique ID: 9616295 Medline TA: Int J Clin Oncol Country: Japan |
Other Details:
|
Languages: eng Pagination: 201-5 Citation Subset: IM |
Affiliation:
|
Department of Gynecology, Ibaraki Prefectural Central Hospital, 6528 Koibuchi, Kasama, Ibaraki 309-1793, Japan. ki-nagai@chubyoin.pref.ibaraki.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angiofibroma
/
diagnosis*,
pathology,
radiography,
surgery Biopsy Diagnosis, Differential Female Humans Immunohistochemistry Middle Aged Myxoma / diagnosis* Tomography, X-Ray Computed Vulvar Neoplasms / diagnosis*, pathology, radiography, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ventriculosinus shunt.
Next Document: Angioimmunoblastic T-cell lymphoma and membranous nephropathy: a still unreported association.