Document Detail


Huge fetal sacrococcygeal teratoma with a completely formed eye and intratumoral DNA ploidy heterogeneity.
MedLine Citation:
PMID:  9841706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Preterm infants and newborns with sacrococcygeal teratomas are at high risk for prenatal and perinatal complications. The prognosis depends on size and histology of the tumor, degree of prematurity, associated malformations, route of delivery, and prompt and complete surgical removal. Virtually any tissue can be present in a sacrococcygeal teratoma, but to date, ocular lens has been documented only as lentinoids (lens-like cells), whereas flow-cytometric data have been variably interpreted. We describe a case of a sacrococcygeal teratoma in an infant of 29 weeks gestational age that is remarkable for the weight (4500 g), the presence of a completely formed eye, and intratumoral DNA ploidy heterogeneity.
Authors:
C Sergi; V Ehemann; B Beedgen; O Linderkamp; H F Otto
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  2     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    1999 Jan-Feb
Date Detail:
Created Date:  1999-03-16     Completed Date:  1999-03-16     Revised Date:  2006-05-08    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  50-7     Citation Subset:  IM    
Affiliation:
Institute of Pathology, University of Heidelberg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Choristoma / diagnosis,  genetics*,  pathology
DNA / chemistry
Eye*
Female
Fetal Diseases / diagnosis,  genetics*,  pathology
Flow Cytometry
Gestational Age
Haploidy
Humans
Infant, Newborn
Infant, Premature
Prenatal Diagnosis
Sacrococcygeal Region
Teratoma / diagnosis,  genetics*,  pathology
Chemical
Reg. No./Substance:
9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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