| How we are born. | |
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MedLine Citation:
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PMID: 20364092 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Human reproduction is relatively inefficient. Nearly 30% of pregnancies result in spontaneous losses, which are both a clinical problem and a psychological stress to the families involved. Furthermore, although the human population is growing rapidly and is predicted to reach 9 billion by 2050, 15% of couples worldwide are childless because of infertility. Many underlying causes of infertility have been overcome by assisted reproductive technologies such as in vitro fertilization, yet pregnancy success rates using such approaches remain disappointingly low. Since mechanistic approaches to study human reproductive processes are ethically restricted, future advances in fertility treatment and the development of new contraceptives rely predominantly on the study of the factors influencing reproduction in model systems. The articles in this Reproductive Biology Review series present updates on the current understanding of various reproductive processes in model systems and raise questions that need to be addressed if we are to improve human reproductive health. |
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Authors:
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Sudhansu K Dey |
Publication Detail:
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Type: Journal Article; Review Date: 2010-04-01 |
Journal Detail:
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Title: The Journal of clinical investigation Volume: 120 ISSN: 1558-8238 ISO Abbreviation: J. Clin. Invest. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-05 Completed Date: 2010-04-21 Revised Date: 2012-02-07 |
Medline Journal Info:
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Nlm Unique ID: 7802877 Medline TA: J Clin Invest Country: United States |
Other Details:
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Languages: eng Pagination: 952-5 Citation Subset: AIM; IM |
Affiliation:
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Cincinnati Children's Research Foundation, Division of Reproductive Sciences, MLC 7045, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA. sk.dey@cchmc.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Embryo Implantation Female Humans Male Placenta / physiology Pregnancy Reproduction / physiology* Sperm-Ovum Interactions |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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