Document Detail

How to use a review article: prophylactic endoscopic sclerotherapy for esophageal varices. Evidence Based Critical Care Medicine Group.
MedLine Citation:
PMID:  9559606     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the validity of a meta-analysis about sclerotherapy for the primary prevention of bleeding from esophageal varices, to interpret the results, and discuss whether they apply in practice. DATA SOURCES: Critical appraisal techniques for systematic reviews. DATA EXTRACTION: Systematic reviews are distinct from narrative reviews in that they answer specific clinical questions, and have explicit and reproducible methods for searching, selecting, and appraising the primary studies, to create the most valid synthesis of the evidence. DATA SYNTHESIS: Meta-analyses are systematic reviews containing a critical appraisal and statistical summary of individual study results and their confidence limits, whereas qualitative systematic reviews provide a narrative executive summary of study results. CONCLUSIONS: High-quality systematic reviews are being used increasingly to guide practice, strengthening the link between research results and improved health outcomes. Understanding their strengths and limitations helps us to use them appropriately in practice.
D J Cook; M M Levy; D K Heyland
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Critical care medicine     Volume:  26     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-05-14     Completed Date:  1998-05-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  692-700     Citation Subset:  AIM; IM    
Department of Medicine, McMaster University, Hamilton, ON, Canada.
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MeSH Terms
Critical Care
Endoscopy, Digestive System
Esophageal and Gastric Varices / therapy*
Evidence-Based Medicine*
Gastrointestinal Hemorrhage / etiology,  prevention & control
Meta-Analysis as Topic*
Middle Aged
Review Literature as Topic
Sclerotherapy* / adverse effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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