Document Detail


How to use... Alkaline phosphatase in neonatology.
MedLine Citation:
PMID:  22761487     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Alkaline phosphatase (ALP) is regularly measured in clinical practice. Changes in serum levels are observed in a number of clinical conditions. In neonatology, it has been proposed as a useful marker for both a diagnosis and an indication of the severity of metabolic bone disease (MBD) in infants born preterm. Nutritional practices, aimed at reducing the occurrence or severity of MBD, have led to ALP being proposed as a stand-alone means of monitoring treatment. The current evidence does not support this use: ALP only achieves usefulness in a diagnostic and monitoring capacity when combined with other serum and imaging techniques.
Authors:
Robert J Tinnion; Nicholas D Embleton
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-3
Journal Detail:
Title:  Archives of disease in childhood. Education and practice edition     Volume:  -     ISSN:  1743-0593     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101220684     Medline TA:  Arch Dis Child Educ Pract Ed     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Newcastle Neonatal Service, Newcastle upon Tyne, UK.
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