Document Detail

How to measure and interpret volumetric measures of preload.
MedLine Citation:
PMID:  17468562     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: To update the situation over the past few years on the clinical application of volumetric measures of preload in critically ill patients. RECENT FINDINGS: Cardiac filling pressures monitoring is unreliable for assessing cardiac preload in mechanically ventilated critically ill patients. The transpulmonary dilution indicator technique was shown to better identify preload than pulmonary arterial catheterization. Measuring static preload index as intrathoracic blood volume or global end diastolic volume provides a good preload index, either in experimental or in different clinical settings. SUMMARY: Volumetric measures of preload are good preload indexes. These data are to be interpreted together with the clinical patient's condition, conventional hemodynamic data and the course of illness in critically ill patients. In order to evaluate whether the application of a predefined therapy algorithm based on volumetric monitoring can improve patients' outcome, more studies are needed.
Giorgio Della Rocca; Maria Gabriella Costa; Paolo Pietropaoli
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in critical care     Volume:  13     ISSN:  1531-7072     ISO Abbreviation:  Curr Opin Crit Care     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-04-30     Completed Date:  2008-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504454     Medline TA:  Curr Opin Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  297-302     Citation Subset:  IM    
Department of Anesthesia and Intensive Care Medicine, University of Udine, Udine, Italy.
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MeSH Terms
Blood Volume Determination / methods
Critical Illness
Heart Function Tests / methods*
Stroke Volume*
Thermodilution / methods

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