Document Detail

How to interpret data from the superficial femoral artery stenting trials and registries.
MedLine Citation:
PMID:  20826290     Owner:  NLM     Status:  MEDLINE    
Recent advances in endovascular technologies have made catheter-based interventions a preferred treatment strategy in patients with intermittent claudication or ischemic rest pain of the lower extremity. Although the current body of literature is inundated with clinical reports favoring countless endovascular devices and treatment techniques for femoropopliteal occlusive disease, analysis of available clinical reports regarding femoropopliteal lesions can be an overwhelming undertaking. In this report, we examine various challenges associated with data interpretation of clinical literature on endovascular treatment of femoropopliteal occlusive disease. Particular attention is focused on prospective randomized trials and clinical registries evaluating treatment efficacy of self-expanding nitinol stent implantation in femoropopliteal lesions. Prospective trials on the efficacy of drug-eluting stent placement and covered stent implantation of the superficial femoral artery are also discussed. Understanding current literature related to prospective randomized trials on femoropopliteal disease interventions is important to formulate an optimal treatment strategy based on appropriate patient selection and disease stratification so that successful treatment outcome can be achieved.
Peter H Lin; Sarah M Weakley; Panagiotis Kougias
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Seminars in vascular surgery     Volume:  23     ISSN:  1558-4518     ISO Abbreviation:  Semin Vasc Surg     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-09     Completed Date:  2010-12-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809602     Medline TA:  Semin Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  138-47     Citation Subset:  IM    
Copyright Information:
(c) 2010 Elsevier Inc. All rights reserved.
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, 1709 Dryden Road, Suite 1500, Houston, TX 77030, USA.
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MeSH Terms
Arterial Occlusive Diseases / therapy*
Constriction, Pathologic
Data Interpretation, Statistical
Device Approval
Drug-Eluting Stents
Endovascular Procedures / adverse effects,  instrumentation*,  statistics & numerical data
Evidence-Based Medicine* / statistics & numerical data
Femoral Artery*
Popliteal Artery*
Prosthesis Design
Randomized Controlled Trials as Topic* / statistics & numerical data
Registries* / statistics & numerical data
Research Design
Treatment Outcome
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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