Document Detail

How to improve the effectiveness of transurethral resection in nonmuscle invasive bladder cancer?
MedLine Citation:
PMID:  19571756     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: The high rate of early recurrences in nonmuscle invasive bladder cancer is considered to be strongly related to the effectiveness of transurethral resection (TUR). The aim of this article is to review methods, currently available or in development, that aim at improving TUR, with an emphasis on studies over the past year. RECENT FINDINGS: It has been shown that re-TUR diminishes staging error and improves local tumour control. However, instead of simply repeating the standard procedure, it makes more sense to improve the technique itself. Modifications in TUR equipment, such as bipolar resection and laser treatment, mainly have the potential to reduce complication rates and possibly thereby improve the effectiveness of TUR. New imaging techniques that can be used during TUR such as narrow-band imaging and optical coherence tomography seem promising, whereas photodynamic diagnosis has already proven its potential role in improving the effectiveness of TUR. SUMMARY: The currently available techniques of re-TUR and photodynamic diagnosis have demonstrated potential to improve effectiveness of TUR and should be used in selected cases. New techniques such as narrow-band imaging and optical coherence tomography seem promising, but more evidence is needed before these methods can be implemented in daily practice.
Evelyne C C Cauberg; Jean J M C H de la Rosette; Theo M de Reijke
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in urology     Volume:  19     ISSN:  1473-6586     ISO Abbreviation:  Curr Opin Urol     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-04     Completed Date:  2009-11-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200621     Medline TA:  Curr Opin Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  504-10     Citation Subset:  IM    
Department of Urology, Academic Medical Center Amsterdam, The Netherlands.
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MeSH Terms
Fluorescent Dyes / diagnostic use
Laser Therapy
Tomography, Optical Coherence
Urinary Bladder Neoplasms / diagnosis,  surgery*
Urologic Surgical Procedures / methods*
Reg. No./Substance:
0/Fluorescent Dyes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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