Document Detail

How to Discriminate between Computer-Aided and Computer-Hindered Decisions: A Case Study in Mammography.
MedLine Citation:
PMID:  23300205     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Computer aids can affect decisions in complex ways, potentially even making them worse; common assessment methods may miss these effects. We developed a method for estimating the quality of decisions, as well as how computer aids affect it, and applied it to computer-aided detection (CAD) of cancer, reanalyzing data from a published study where 50 professionals ("readers") interpreted 180 mammograms, both with and without computer support.
METHOD: . We used stepwise regression to estimate how CAD affected the probability of a reader making a correct screening decision on a patient with cancer (sensitivity), thereby taking into account the effects of the difficulty of the cancer (proportion of readers who missed it) and the reader's discriminating ability (Youden's determinant). Using regression estimates, we obtained thresholds for classifying a posteriori the cases (by difficulty) and the readers (by discriminating ability).
RESULTS: . Use of CAD was associated with a 0.016 increase in sensitivity (95% confidence interval [CI], 0.003-0.028) for the 44 least discriminating radiologists for 45 relatively easy, mostly CAD-detected cancers. However, for the 6 most discriminating radiologists, with CAD, sensitivity decreased by 0.145 (95% CI, 0.034-0.257) for the 15 relatively difficult cancers.
CONCLUSIONS: . Our exploratory analysis method reveals unexpected effects. It indicates that, despite the original study detecting no significant average effect, CAD helped the less discriminating readers but hindered the more discriminating readers. Such differential effects, although subtle, may be clinically significant and important for improving both computer algorithms and protocols for their use. They should be assessed when evaluating CAD and similar warning systems.
Andrey A Povyakalo; Eugenio Alberdi; Lorenzo Strigini; Peter Ayton
Related Documents :
24914835 - Prostate cancer epidemiology.
25018385 - 0400 occupational exposure to extremely low frequency magnetic fields or electric sho...
23393415 - The effects of extremely low-frequency magnetic fields on melatonin and cortisol, two m...
23074405 - Robotic-assisted minimally invasive surgery for gynecologic and urologic oncology: an e...
11407595 - The role of p53 in human cancer.
23568405 - Predictors of risk-based medical follow-up: a report from the childhood cancer survivor...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical decision making : an international journal of the Society for Medical Decision Making     Volume:  33     ISSN:  1552-681X     ISO Abbreviation:  Med Decis Making     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8109073     Medline TA:  Med Decis Making     Country:  United States    
Other Details:
Languages:  eng     Pagination:  98-107     Citation Subset:  IM    
Centre for Software Reliability, City University London, Northampton Square, London, UK (AAP, EA, LS).
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Incorporating patient decision AIDS into standard clinical practice in an integrated delivery system...
Next Document:  Motor and premotor cortices in subcortical stroke: proton magnetic resonance spectroscopy measures a...