Document Detail


How to Differentiate Benign versus Malignant Cardiac and Paracardiac 18F FDG Uptake at Oncologic PET/CT.
MedLine Citation:
PMID:  21918045     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Patients undergoing 2-[fluorine 18]fluoro-2-deoxy-d-glucose (FDG) whole-body oncologic positron emission tomography (PET)/computed tomography (CT) are studied while fasting. Cardiac FDG uptake in fasted patients has been widely reported as variable. It is important to understand the normal patterns of cardiac FDG activity that can be seen in oncologic FDG PET/CT studies. These include focal and regional patterns of increased FDG myocardial activity. Focal activity can be observed in papillary muscles, the atria, the base, and the distal anteroapical region of the left ventricle. Regional increased cardiac FDG activity may be diffuse or localized in the posterolateral wall or the base of the left ventricle. Abnormal patterns of cardiac FDG activity not related to malignancy include those associated with lipomatous hypertrophy of the interatrial septum, epicardial and pericardial fat, increased atrial activity associated with atrial fibrillation or a prominent crista terminalis, cardiac sarcoidosis, endocarditis, myocarditis, and pericarditis. Knowledge of these patterns of cardiac FDG activity is important to be able to recognize malignant disease involving the paracardiac spaces, myocardium, and pericardium. With a better understanding of the range of normal and abnormal patterns of cardiac FDG activity, important benign and malignant diseases involving the heart and pericardium can be recognized and diagnosed. © RSNA, 2011.
Authors:
Alan H Maurer; Mark Burshteyn; Lee P Adler; Robert M Steiner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  31     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-09-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1287-305     Citation Subset:  IM    
Affiliation:
Department of Radiology, Temple University School of Medicine, 3401 N Broad St, Parkinson Pavilion, 1st Floor, Philadelphia, PA 19140.
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