Document Detail


How the skin can tell time.
MedLine Citation:
PMID:  19369933     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The mammalian central circadian pacemaker, which is located in the suprachiasmatic nucleus (SCN) of the hypothalamus, synchronizes and entrains clocks found in peripheral tissues. Skin harbors an active circadian clock that is under the influence of the central clock. This clock, which probably operates in most-perhaps all-types of skin cells, may influence the regulation of several circadian physiological phenomena, including cell proliferation.
Authors:
Mikhail Geyfman; Bogi Andersen
Related Documents :
15273643 - Lack of genotoxicity of formocresol, paramonochlorophenol, and calcium hydroxide on mam...
3173403 - Deoxynucleoside triphosphate pool perturbation is not a general feature in mutagen-trea...
109543 - Aging of melanocytes.
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  129     ISSN:  1523-1747     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-16     Completed Date:  2009-05-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1063-6     Citation Subset:  IM    
Affiliation:
Departments of Medicine and Biological Chemistry, University of California, Irvine, California 92697, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cell Proliferation
Circadian Rhythm / physiology*
Fibroblasts / cytology,  physiology
Keratinocytes / cytology*,  physiology
Mice
Models, Animal
Photoperiod
Seasons
Skin / cytology*
Skin Physiological Phenomena*
Suprachiasmatic Nucleus / physiology
Temperature
Comments/Corrections
Comment On:
J Invest Dermatol. 2009 May;129(5):1225-31   [PMID:  19037239 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Peroxisome proliferator-activating receptors: a new way to treat melanoma?
Next Document:  Scarring alopecia and the PPAR-gamma connection.