Document Detail

How should we manage adverse intradialytic blood pressure changes?
MedLine Citation:
PMID:  22578675     Owner:  NLM     Status:  In-Data-Review    
Variations in intradialytic blood pressure (BP) are a common and predictable occurrence in ESRD patients. These are caused by a decrease in blood volume provoked by ultrafiltration, lack of normal compensatory responses to fluid removal, underlying cardiac disease, and electrolyte changes that may adversely affect cardiovascular function. Intradialytic hypotension is the most frequent complication of the hemodialysis (HD) procedure and is fundamentally a consequence of an ultrafiltration rate that surpasses mechanisms activated to avert a decline in BP. Intradialytic hypertension is a less well-understood problem that has been recently associated with increased mortality. Fundamental patient characteristics and components of the HD procedure are involved in the pathophysiology of intradialytic hypotension and intradialytic hypertension. Correction of patient factors, modulation of HD prescription, and management of pharmacologic agents are the strategies to deal with adverse intradialytic BP changes.
Sergio F F Santos; Aldo J Peixoto; Mark A Perazella
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in chronic kidney disease     Volume:  19     ISSN:  1548-5609     ISO Abbreviation:  Adv Chronic Kidney Dis     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101209214     Medline TA:  Adv Chronic Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  158-65     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 National Kidney Foundation, Inc. All rights reserved.
Division of Nephrology, State University of Rio de Janeiro, Rio de Janeiro, Brazil; Section of Nephrology, Yale University School of Medicine, New Haven, CT; and Medical Service and Renal Section, VA Connecticut Healthcare System, West Haven, CT.
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