Document Detail

How should the patient with multiple endocrine neoplasia type 1 (MEN 1) be followed?
MedLine Citation:
PMID:  19552677     Owner:  NLM     Status:  MEDLINE    
Multiple endocrine neoplasia type 1 (MEN 1) is a complex multi-system disease manifesting a diverse range of primary and secondary metabolic and neoplastic disorders. It is possible to improve patient prognosis by early disease detection and treatment. Regular biochemical and radiological screening for parathyroid, gastro-enteropancreatic, pituitary, intrathorasic and adrenal lesions forms the basis of surveillance. The likelihood of adverse sequelea such as renal and bone disease resulting from hyperparathyroidism, severe peptic ulceration and gastric carcinoidosis secondary to hypergastrinaemia can be ameliorated by early detection and management.
John Burgess
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-06-22
Journal Detail:
Title:  Clinical endocrinology     Volume:  72     ISSN:  1365-2265     ISO Abbreviation:  Clin. Endocrinol. (Oxf)     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-06     Completed Date:  2010-03-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346653     Medline TA:  Clin Endocrinol (Oxf)     Country:  England    
Other Details:
Languages:  eng     Pagination:  13-6     Citation Subset:  IM    
Department of Endocrinology, Royal Hobart Hospital, Hobart, TAS, Australia.
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MeSH Terms
Cardiovascular Diseases / diagnosis,  etiology,  prevention & control
Continuity of Patient Care*
Follow-Up Studies
Hyperparathyroidism / diagnosis,  etiology,  prevention & control,  therapy
Multiple Endocrine Neoplasia Type 1 / complications,  diagnosis,  etiology,  therapy*
Neoplasms / diagnosis,  etiology,  therapy
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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