Document Detail


How safe are the xenogeneic hemostats?--Report of a case of severe systemic allergic reaction.
MedLine Citation:
PMID:  7640472     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report herein the unusual case of a 55-year-old woman who developed a severe systemic allergy to Avitene (microfibrillar collagen hydrochloride), a xenogeneic agent sometimes used for topical hemostasis in laparoscopic cholecystectomy. The patient developed fever, general fatigue, mild liver dysfunction, and prominent eosinophilia postoperatively. A skin allergy test confirmed that these abnormal findings were attributable to an allergic reaction to Avitene.
Authors:
K Kitamura; R Yasuoka; M Ohara; M Shimotsuma; A Hagiwara; T Yamane; T Yamaguchi; T Takahashi
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgery today     Volume:  25     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1995  
Date Detail:
Created Date:  1995-09-19     Completed Date:  1995-09-19     Revised Date:  2006-08-03    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  433-5     Citation Subset:  IM    
Affiliation:
First Department of Surgery, Kyoto Prefectural University of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Abdominal Abscess / diagnosis
Cholecystectomy, Laparoscopic
Collagen / adverse effects*
Diagnosis, Differential
Drug Hypersensitivity* / diagnosis
Female
Hemostasis, Surgical
Hemostatics / adverse effects*
Humans
Middle Aged
Postoperative Complications / diagnosis
Chemical
Reg. No./Substance:
0/Hemostatics; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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