Document Detail

How reproducible is home-based 24-hour ambulatory monitoring of motor activity in patients with multiple sclerosis?
MedLine Citation:
PMID:  20875511     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the reproducibility of 24-hour monitoring of motor activity in patients with multiple sclerosis (MS). DESIGN: Test-retest design; 6 research assistants visited the participants twice within 1 week in the home situation. SETTING: General community. PARTICIPANTS: A convenience sample of ambulatory patients (N=43; mean age ± SD, 48.7±7.0y; 30 women; median Expanded Disability Status Scale scores, 3.5; interquartile range, 2.5) were recruited from the outpatient clinic of a university medical center. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Dynamic activity and static activity parameters were recorded by using a portable data logger and classified continuously for 24 hours. Reproducibility was determined by calculating intraclass correlation coefficients (ICCs) for test-retest reliability and by applying the Bland-Altman method for agreement between the 2 measurements. The smallest detectable change (SDC) was calculated based on the standard error of measurement. RESULTS: Test-retest reliability expressed by the ICC(agreement) was .72 for dynamic activity, .74 for transitions, .77 for walking, .71 for static activity, .67 for sitting, .62 for standing, and .55 for lying. Bland and Altman analysis indicated no systematic differences between the first and second assessment for dynamic and static activity. Measurement error expressed by the SDC was 1.23 for dynamic activity, 66 for transitions, .99 for walking, 1.52 for static activity, 4.68 for lying, 3.95 for sitting, and 3.34 for standing. CONCLUSIONS: The current study shows that with 24-hour monitoring, a reproducible estimate of physical activity can be obtained in ambulatory patients with MS.
Marc B Rietberg; Erwin E van Wegen; Bernard M Uitdehaag; Henrica C de Vet; Gert Kwakkel
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  91     ISSN:  1532-821X     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-29     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1537-41     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Department of Rehabilitation Medicine, Research Institute MOVE, Amsterdam, The Netherlands.
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MeSH Terms
Academic Medical Centers
Activities of Daily Living
Middle Aged
Monitoring, Ambulatory / methods*
Motor Activity*
Multiple Sclerosis / rehabilitation*
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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