Document Detail

How often is a low 5-min Apgar score in term newborns due to asphyxia?
MedLine Citation:
PMID:  16621222     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate how often low 5-min Apgar scores (AS(5-min)) at term are associated with asphyxia. STUDY DESIGN: A cohort- and case-control study, including all 183 term infants with AS(5-min) below 7 born at Lund University Hospital during 1993-2002, antepartum deaths excluded. The control group included 183 randomly selected term newborns with AS(5-min) 9-10. Cardiotocography (CTG) traces were assessed blinded to group and outcome. Obstetric and pediatric files were reviewed. RESULTS: After excluding infants with severe malformations, indications of hypoxia were found at the following rates in cases with AS(5-min) below 4 (N = 30), scores 4-6 (N = 143), and controls (N = 182)-abnormal admission CTG: 38%, 8% and 0.6%; abnormal CTG before birth: 88%, 69% and 18%; obstetrical catastrophe: 28%, 6% and 0.6%; interventions for fetal distress: 83%, 48% and 9%; cord artery pH below 7.15: 69%, 54% and 7%; hypoxic ischemic encephalopathy or hypoxic death: 70%, 14% and none. All differences between each case group and controls were statistically significant (p < 0.0001). CONCLUSIONS: In the absence of severe malformations, the vast majority of AS(5-min) below 4, and at least half of scores 4-6 could be attributed to birth asphyxia. Signs of hypoxia usually appeared during labor, but were present at admission in 38% of cases with AS(5-min) below 4.
Linda Hogan; Ingemar Ingemarsson; Kristina Thorngren-Jerneck; Andreas Herbst
Publication Detail:
Type:  Journal Article     Date:  2006-04-18
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  130     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-22     Completed Date:  2007-03-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  169-75     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Lund University Hospital, Sweden.
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MeSH Terms
Acidosis / diagnosis
Apgar Score*
Asphyxia Neonatorum / diagnosis*
Case-Control Studies
Cohort Studies
Delivery, Obstetric / adverse effects
Fetal Blood / chemistry*
Fetal Distress / etiology*
Fetal Hypoxia / diagnosis*
Hypoxia-Ischemia, Brain / diagnosis
Infant, Newborn
Predictive Value of Tests
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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