| How many measurements are needed to provide reliable information in terms of the ambulatory arterial stiffness index? the Ohasama study. | |
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MedLine Citation:
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PMID: 21124327 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The aim of this study was to investigate how frequent ambulatory blood pressure (ABP) readings need to be obtained to reproduce the ambulatory arterial stiffness index (AASI) and pulse pressure (PP) without loss of information. We compared concordance from full and reduced ABP recordings. We recorded 24-h ABP at 30-min intervals in 1542 residents of Ohasama, Japan (baseline age, 40-93 years; 63.4% women). We randomly excluded up to 16 readings per recording or we selected readings at fixed 1- or 2-h intervals. Using full recordings as reference, we computed for the reduced recordings repeatability coefficient by Bland and Altman's approach. By Cox regression, we also calculated multivariate-adjusted hazard ratios for cardiovascular mortality. The median number of ABP readings per recording was 46. Randomly excluding more readings reduced the concordance of AASI, but not PP. Selecting blood pressure readings at 1- or 2-h intervals produced mean values of AASI and PP, which significantly differed from those in full recordings. During follow-up (median, 13.3 years) 126 cardiovascular deaths occurred. Across quartiles, AASI significantly predicted cardiovascular mortality in a U-shaped manner. AASI lost its prognostic significance when the number of randomly excluded readings increased from 8 to 16 or when the interval between readings was 1 h or longer. Compared with PP, AASI is less reproducible when the number of readings in ABP decreases, but this does not affect the predictive accuracy of AASI for cardiovascular mortality, until the median number of readings per ABP recording is less than ∼35. |
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Authors:
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Masahiro Kikuya; Jan A Staessen; Takayoshi Ohkubo; Lutgarde Thijs; Kei Asayama; Michihiro Satoh; Takanao Hashimoto; Takuo Hirose; Hirohito Metoki; Taku Obara; Ryusuke Inoue; Yan Li; Eamon Dolan; Haruhisa Hoshi; Kazuhito Totsune; Hiroshi Satoh; Ji-Guang Wang; Eoin O'Brien; Yutaka Imai |
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Publication Detail:
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Type: Journal Article Date: 2010-12-02 |
Journal Detail:
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Title: Hypertension research : official journal of the Japanese Society of Hypertension Volume: 34 ISSN: 1348-4214 ISO Abbreviation: Hypertens. Res. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9307690 Medline TA: Hypertens Res Country: England |
Other Details:
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Languages: eng Pagination: 314-8 Citation Subset: IM |
Affiliation:
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1] Tohoku University Graduate School of Medicine and Pharmaceutical Sciences, Sendai, Japan [2] Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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