| How long should patients be followed after molar pregnancy? Analysis of serum hCG follow-up data. | |
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MedLine Citation:
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PMID: 14687748 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We analyzed human chorionic gonadotropin (hCG) follow-up data of patients with molar pregnancy. Women often do not complete recommended post-disease screening. Our purpose was to determine if continuing follow up of uncomplicated molar cases beyond attaining undetectable hCG levels is necessary for detecting relapse of gestational trophoblastic disease. STUDY DESIGN: One hundred fifty patients treated at Hungarian National Health Center were analyzed. Those who developed persistent disease before hCG had become undetectable were excluded from further analysis (n=24; 16%). RESULTS: Among 126 uncomplicated cases, 72 patients (57%) completed follow up, and 54 (43%) discontinued their protocol before it had been completed. Of 120 patients who achieved at least one undetectable hCG level, none had any evidence of relapse. CONCLUSION: In uncomplicated hydatidiform mole, our analysis indicates that once undetectable serum hCG levels are attained, relapse is unlikely. Although further monthly checks are advisable, the likelihood of recurrence appears very low. |
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Authors:
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Jozsef Batorfi; Gyorgy Vegh; Janos Szepesi; Ivan Szigetvari; Jozsef Doszpod; Vilmos Fulop |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 112 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 2004 Jan |
Date Detail:
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Created Date: 2003-12-22 Completed Date: 2004-02-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: Ireland |
Other Details:
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Languages: eng Pagination: 95-7 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, National Health Center, 35 Szabolcs Street, Budapest 1135, Hungary. batorfijozsef@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Chorionic Gonadotropin / analysis, blood* Cohort Studies Combined Modality Therapy Female Follow-Up Studies Humans Hydatidiform Mole / diagnosis*, therapy Middle Aged Neoplasm Recurrence, Local / diagnosis* Pregnancy Probability Retrospective Studies Risk Assessment Sensitivity and Specificity Time Factors Treatment Outcome Tumor Markers, Biological / analysis* Uterine Neoplasms / diagnosis*, therapy |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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