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How is electrocardiogram influenced by electroconvulsive therapy in males and females?
MedLine Citation:
PMID:  21343714     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVES: : We aimed to investigate and compare the P duration and P dispersion (Pd) between male and female patients with a primary diagnosis of chronic schizophrenia disorder before and after the electroconvulsive therapy (ECT) period.
METHODS: : We obtained electrocardiograms of 50 healthy young volunteers which included 25 female (group F, n = 25) and 25 male patients (group M, n = 25). We measured minimum and maximum P wave durations (Pmin, Pmax) and Pd in milliseconds. Electrocardiography was performed before electroconvulsive therapy (ECT) and immediately after the ECT period after awakening. A 12-lead surface electrocardiogram was obtained from each subject in the supine position.
RESULTS: : The post-ECT P duration was significantly longer than the pre-ECT P duration in groups F and M (P = 0.01 and P = 0.008, respectively). The post-ECT Pd was significantly longer than the pre-ECT Pd in groups F and M (P = 0.0001 in both groups). A higher correlation (r) in group M was observed between the pre-ECT Pd and post-ECT P duration than in group F (r = 0.538, P = 006 in group M; r = 0.349, P = 08 in group F). There was no significant difference between the groups regarding hemodynamics.
CONCLUSIONS: : Electroconvulsive therapy in both sexes may influence atrial conduction as evidenced by the significantly prolonged Pmax and Pd in patients with a primary diagnosis of schizophrenia disorder.
Ayse Mizrak; Ibrahim Sari; Levent Sahin; Suleyman Ganidagli; Haluk A Savas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of ECT     Volume:  27     ISSN:  1533-4112     ISO Abbreviation:  J ECT     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808943     Medline TA:  J ECT     Country:  United States    
Other Details:
Languages:  eng     Pagination:  73-6     Citation Subset:  IM    
From the Departments of *Anesthesiology and Reanimation, †Cardiology, and ‡Psychiatry, Gaziantep University School of Medicine, Gaziantep, Turkey.
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