| How does a hypha grow? The biophysics of pressurized growth in fungi. | |
| | |
MedLine Citation:
|
PMID: 21643041 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The mechanisms underlying the growth of fungal hyphae are rooted in the physical property of cell pressure. Internal hydrostatic pressure (turgor) is one of the major forces driving the localized expansion at the hyphal tip which causes the characteristic filamentous shape of the hypha. Calcium gradients regulate tip growth, and secretory vesicles that contribute to this process are actively transported to the growing tip by molecular motors that move along cytoskeletal structures. Turgor is controlled by an osmotic mitogen-activated protein kinase cascade that causes de novo synthesis of osmolytes and uptake of ions from the external medium. However, as discussed in this Review, turgor and pressure have additional roles in hyphal growth, such as causing the mass flow of cytoplasm from the basal mycelial network towards the expanding hyphal tips at the colony edge. |
| | |
Authors:
|
Roger R Lew |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-06 |
Journal Detail:
|
Title: Nature reviews. Microbiology Volume: - ISSN: 1740-1534 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-6-6 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101190261 Medline TA: Nat Rev Microbiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Biology, York University, 4700 Keele Street, Toronto, Ontario M3J 1P3, Canada. planters@yorku.ca. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: New insights into visceral hypersensitivity--clinical implications in IBS.
Next Document: Direct femtosecond laser waveguide writing inside zinc phosphate glass.