Document Detail

How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.
MedLine Citation:
PMID:  21532972     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To study substance use and psychiatric disorders among prescription opioid users, heroin users, and non-opioid drug users in a national sample of adults.
METHODS: Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (N=43,093).
RESULTS: Four groups were identified among 9140 illicit or non-prescribed drug users: heroin-other opioid users (1.0%; used heroin and other opioids), other opioid-only users (19.8%; used other opioids but never heroin), heroin-only users (0.5%; used heroin but never other opioids), and non-opioid drug users (78.7%; used drugs but never heroin or other opioids). After adjusting for variations in socioeconomic characteristics, history of substance abuse treatment, and familial substance abuse, heroin-other opioid users had greater odds of several substance use disorders (cocaine, hallucinogen, sedative, amphetamine, and tranquilizer) as compared with the other groups; heroin-only users had reduced odds of sedative and tranquilizer use disorders as compared with other opioid-only users. Non-opioid drug users had reduced odds of all substance use disorders and other mental disorders (mood, anxiety, pathological gambling, and personality) as compared with other opioid-only users. Past-year other opioid-only users also reported slightly lower scores on quality of life than past-year non-opioid drug users.
CONCLUSIONS: All opioid use groups had higher rates of substance use disorders than non-opioid drug users, and these rates were particularly elevated among heroin-other opioid users. Findings suggest the need to distinguish between these four groups in research and treatment as they may have different natural histories and treatment needs.
Li-Tzy Wu; George E Woody; Chongming Yang; Dan G Blazer
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of addiction medicine     Volume:  5     ISSN:  1932-0620     ISO Abbreviation:  J Addict Med     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-07-19     Completed Date:  2011-09-06     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  101306759     Medline TA:  J Addict Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  28-35     Citation Subset:  IM    
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MeSH Terms
Anxiety Disorders / epidemiology,  psychology,  rehabilitation
Cross-Sectional Studies
Health Surveys
Heroin Dependence / epidemiology,  psychology*,  rehabilitation*
Interview, Psychological
Mental Disorders / epidemiology,  psychology*,  rehabilitation*
Middle Aged
Mood Disorders / epidemiology,  psychology,  rehabilitation
Narcotics / therapeutic use*
Opioid-Related Disorders / epidemiology,  psychology*,  rehabilitation*
Personality Disorders / epidemiology,  psychology,  rehabilitation
Quality of Life / psychology
Street Drugs*
Substance-Related Disorders / epidemiology,  psychology*,  rehabilitation*
United States
Young Adult
Grant Support
DA013043/DA/NIDA NIH HHS; DA017009/DA/NIDA NIH HHS; DA0196623/DA/NIDA NIH HHS; DA019901/DA/NIDA NIH HHS; DA026652/DA/NIDA NIH HHS; DA027503/DA/NIDA NIH HHS; HHSN271200522071C//PHS HHS; K05 DA017009/DA/NIDA NIH HHS; K05 DA017009-08/DA/NIDA NIH HHS; R01 DA019623/DA/NIDA NIH HHS; R01 DA019623-03/DA/NIDA NIH HHS; R01 DA019901/DA/NIDA NIH HHS; R01 DA019901-02/DA/NIDA NIH HHS; R01 DA019901-03/DA/NIDA NIH HHS; R01 DA026652/DA/NIDA NIH HHS; R01 DA026652-16A1S1/DA/NIDA NIH HHS; R21 DA027503/DA/NIDA NIH HHS; R21 DA027503-01/DA/NIDA NIH HHS; U10 DA013043/DA/NIDA NIH HHS; U10 DA013043-10/DA/NIDA NIH HHS
Reg. No./Substance:
0/Narcotics; 0/Street Drugs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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