| How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions. | |
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MedLine Citation:
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PMID: 21532972 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To study substance use and psychiatric disorders among prescription opioid users, heroin users, and non-opioid drug users in a national sample of adults. METHODS: Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (N=43,093). RESULTS: Four groups were identified among 9140 illicit or non-prescribed drug users: heroin-other opioid users (1.0%; used heroin and other opioids), other opioid-only users (19.8%; used other opioids but never heroin), heroin-only users (0.5%; used heroin but never other opioids), and non-opioid drug users (78.7%; used drugs but never heroin or other opioids). After adjusting for variations in socioeconomic characteristics, history of substance abuse treatment, and familial substance abuse, heroin-other opioid users had greater odds of several substance use disorders (cocaine, hallucinogen, sedative, amphetamine, and tranquilizer) as compared with the other groups; heroin-only users had reduced odds of sedative and tranquilizer use disorders as compared with other opioid-only users. Non-opioid drug users had reduced odds of all substance use disorders and other mental disorders (mood, anxiety, pathological gambling, and personality) as compared with other opioid-only users. Past-year other opioid-only users also reported slightly lower scores on quality of life than past-year non-opioid drug users. CONCLUSIONS: All opioid use groups had higher rates of substance use disorders than non-opioid drug users, and these rates were particularly elevated among heroin-other opioid users. Findings suggest the need to distinguish between these four groups in research and treatment as they may have different natural histories and treatment needs. |
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Authors:
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Li-Tzy Wu; George E Woody; Chongming Yang; Dan G Blazer |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Journal of addiction medicine Volume: 5 ISSN: 1932-0620 ISO Abbreviation: J Addict Med Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-07-19 Completed Date: 2011-09-06 Revised Date: 2012-09-24 |
Medline Journal Info:
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Nlm Unique ID: 101306759 Medline TA: J Addict Med Country: United States |
Other Details:
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Languages: eng Pagination: 28-35 Citation Subset: IM |
Affiliation:
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Department of Psychiatry and Behavioral Sciences, School of Medicine, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA. litzy.wu@duke.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anxiety Disorders / epidemiology, psychology, rehabilitation Comorbidity Cross-Sectional Studies Female Health Surveys Heroin Dependence / epidemiology, psychology*, rehabilitation* Humans Interview, Psychological Male Mental Disorders / epidemiology, psychology*, rehabilitation* Middle Aged Mood Disorders / epidemiology, psychology, rehabilitation Narcotics / therapeutic use* Opioid-Related Disorders / epidemiology, psychology*, rehabilitation* Personality Disorders / epidemiology, psychology, rehabilitation Psychopathology Quality of Life / psychology Street Drugs* Substance-Related Disorders / epidemiology, psychology*, rehabilitation* United States Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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DA013043/DA/NIDA NIH HHS; DA017009/DA/NIDA NIH HHS; DA0196623/DA/NIDA NIH HHS; DA019901/DA/NIDA NIH HHS; DA026652/DA/NIDA NIH HHS; DA027503/DA/NIDA NIH HHS; HHSN271200522071C//PHS HHS; K05 DA017009-08/DA/NIDA NIH HHS; R01 DA019623-03/DA/NIDA NIH HHS; R01 DA019901-02/DA/NIDA NIH HHS; R01 DA019901-03/DA/NIDA NIH HHS; R01 DA026652-16A1S1/DA/NIDA NIH HHS; R01 DA026652-19/DA/NIDA NIH HHS; R21 DA027503-01/DA/NIDA NIH HHS; U10 DA013043-10/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Narcotics; 0/Street Drugs |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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