| House dust mites in pediatric atopic dermatitis. | |
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MedLine Citation:
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PMID: 21301766 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate hypersensitivity to Dermatophagoides pteronyssinus (D. pteronyssinus) and D. farinae in pediatric patients with atopic dermatitis (AD), and to assess the therapeutic value of using acaricides with other environmental anti house dust mites (HDM) measures. METHODS: Ninety-eight children with AD were chosen randomly from the Pediatric Allergy Clinic in Al-Noor Hospital, Khalifa branch, Abu Dhabi, United Arab Emirates during the period between January 2008 to January 2009 and were evaluated for severity and chronicity. They were subjected to skin prick test (SPT) including D. pteronyssinus and D. farinae antigens and were also assessed for the therapeutic value of acaricides and environmental anti HDM measures. RESULTS: We found that 74.5% of patients were sensitive to one or both strains of HDM. A highly significant association was found between the severity of the symptoms of AD and its persistence with hypersensitivity to HDM (p=0.001). Acaricides and environmental anti HDM measures can improve patients with mild AD. CONCLUSION: Hypersensitivity to HDM is an important factor for the more acute, more chronic, and more severe AD. Anti HDM measures including the use of acaricides can help control mild AD. We recommend SPT as a part of the work up of patients with AD. The HDM sensitive patients can benefit from anti HDM measures. |
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Authors:
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Tamer M Adham; Safwat A Tawfik; Naglaa M Abdo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Saudi medical journal Volume: 32 ISSN: 0379-5284 ISO Abbreviation: Saudi Med J Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-08 Completed Date: 2011-06-17 Revised Date: 2011-11-25 |
Medline Journal Info:
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Nlm Unique ID: 7909441 Medline TA: Saudi Med J Country: Saudi Arabia |
Other Details:
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Languages: eng Pagination: 177-82 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Ain Shams University, PO Box 46713, Abu Dhabi, United Arab Emirates. drtadham@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acaricides
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therapeutic use* Animals Child Child, Preschool Dermatitis, Atopic / diagnosis, immunology*, prevention & control* Dermatophagoides farinae / immunology* Dermatophagoides pteronyssinus / immunology* Environment Female Humans Male Skin Tests United Arab Emirates |
| Chemical | |
Reg. No./Substance:
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0/Acaricides |
| Comments/Corrections | |
Comment In:
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Saudi Med J. 2011 Oct;32(10):1085; author reply 1085
[PMID:
22008934
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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