Document Detail

House dust mites in pediatric atopic dermatitis.
MedLine Citation:
PMID:  21301766     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate hypersensitivity to Dermatophagoides pteronyssinus (D. pteronyssinus) and D. farinae in pediatric patients with atopic dermatitis (AD), and to assess the therapeutic value of using acaricides with other environmental anti house dust mites (HDM) measures.
METHODS: Ninety-eight children with AD were chosen randomly from the Pediatric Allergy Clinic in Al-Noor Hospital, Khalifa branch, Abu Dhabi, United Arab Emirates during the period between January 2008 to January 2009 and were evaluated for severity and chronicity. They were subjected to skin prick test (SPT) including D. pteronyssinus and D. farinae antigens and were also assessed for the therapeutic value of acaricides and environmental anti HDM measures.
RESULTS: We found that 74.5% of patients were sensitive to one or both strains of HDM. A highly significant association was found between the severity of the symptoms of AD and its persistence with hypersensitivity to HDM (p=0.001). Acaricides and environmental anti HDM measures can improve patients with mild AD.
CONCLUSION: Hypersensitivity to HDM is an important factor for the more acute, more chronic, and more severe AD. Anti HDM measures including the use of acaricides can help control mild AD. We recommend SPT as a part of the work up of patients with AD. The HDM sensitive patients can benefit from anti HDM measures.
Tamer M Adham; Safwat A Tawfik; Naglaa M Abdo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  32     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-08     Completed Date:  2011-06-17     Revised Date:  2011-11-25    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Department of Pediatrics, Ain Shams University, PO Box 46713, Abu Dhabi, United Arab Emirates.
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MeSH Terms
Acaricides / therapeutic use*
Child, Preschool
Dermatitis, Atopic / diagnosis,  immunology*,  prevention & control*
Dermatophagoides farinae / immunology*
Dermatophagoides pteronyssinus / immunology*
Skin Tests
United Arab Emirates
Reg. No./Substance:
Comment In:
Saudi Med J. 2011 Oct;32(10):1085; author reply 1085   [PMID:  22008934 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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