Document Detail


Host response to influenza virus: protection versus immunopathology.
MedLine Citation:
PMID:  20594815     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Host responses play crucial roles in defense against influenza but sometimes these may contribute to immunopathology. Potentially, this may be more important in disease caused by viruses such as avian influenza A H5N1 or the 1918 H1N1 influenza virus rather than with seasonal influenza or pandemic H1N1 2009 (pdmH1N1). Understanding pathogenesis will help develop novel therapeutic options that minimize immunopathology without impairing beneficial host defenses.
Authors:
J S M Peiris; Kenrie P Y Hui; Hui-Ling Yen
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2010-06-30
Journal Detail:
Title:  Current opinion in immunology     Volume:  22     ISSN:  1879-0372     ISO Abbreviation:  Curr. Opin. Immunol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-16     Completed Date:  2010-11-12     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  475-81     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Microbiology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China. malik@hkucc.hku.hk
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MeSH Terms
Descriptor/Qualifier:
Adaptive Immunity
Animals
Birds
CD4-Positive T-Lymphocytes / immunology
CD8-Positive T-Lymphocytes / immunology
Humans
Immunity, Innate / physiology*
Influenza A Virus, H1N1 Subtype / immunology*
Influenza A Virus, H5N1 Subtype / immunology*
Influenza in Birds / immunology,  prevention & control*
Influenza, Human / immunology,  prevention & control*
Grant Support
ID/Acronym/Agency:
HHSN266200700005C//PHS HHS; HHSN2662007005C//PHS HHS
Comments/Corrections

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