Document Detail


Host-range properties of murine xenotropic and ecotropic type-C viruses.
MedLine Citation:
PMID:  176389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Host-range properties of xenotropic (x-tropic) and ecotropic mouse type-C viruses were determined. NB-tropic viruses replicated only in mouse and rat cells, whereas x-tropic viruses, which do not exogenously infect mouse cells, grew in cells from various other mammalian species. Great variability in susceptibilities to x-tropic viruses was demonstrated in cells from heterologous species and in cells from a single species (human). Although rat cells were susceptible to both types of viruses, hamster cells were uniformly resistant. In addition, the x-tropic viruses crossed class barriers to infect cells of avian species but not insect, fish, or reptile cells.
Authors:
H K Oie; E K Russell; J H Dotson; J M Rhoads; A F Gazdar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the National Cancer Institute     Volume:  56     ISSN:  0027-8874     ISO Abbreviation:  J. Natl. Cancer Inst.     Publication Date:  1976 Feb 
Date Detail:
Created Date:  1976-06-02     Completed Date:  1976-06-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503089     Medline TA:  J Natl Cancer Inst     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  423-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Birds
Cells, Cultured
Insects
Mammals
Mice
Rats
Reptiles
Retroviridae / growth & development*
Species Specificity*
Virus Replication

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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