Document Detail


Host interception of bacterial communication signals.
MedLine Citation:
PMID:  19064249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pathogenic Staphylococcus aureus employs a cell-to-cell communication system to control virulence factor expression in the host during infection. In this issue, Peterson et al. (2008) report that host lipoproteins can sequester the S. aureus communication signal and antagonize virulence factor expression and pathogenesis in a murine model of infection.
Authors:
Alexander R Horswill; William M Nauseef
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell host & microbe     Volume:  4     ISSN:  1934-6069     ISO Abbreviation:  Cell Host Microbe     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-09     Completed Date:  2009-01-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101302316     Medline TA:  Cell Host Microbe     Country:  United States    
Other Details:
Languages:  eng     Pagination:  507-9     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. alex-horswill@uiowa.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacterial Proteins / antagonists & inhibitors*
Lipoproteins / immunology*
Mice
Staphylococcal Infections / immunology*
Staphylococcus aureus / pathogenicity*
Chemical
Reg. No./Substance:
0/AgrD protein, Staphylococcus; 0/Bacterial Proteins; 0/Lipoproteins
Comments/Corrections
Comment On:
Cell Host Microbe. 2008 Dec 11;4(6):555-66   [PMID:  19064256 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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