| Host immunologic augmentation for the control of infection. | |
| | |
MedLine Citation:
|
PMID: 8803624 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The emergence of resistance to pharmacologic antimicrobial agents and the desire to increase chemotherapy dose-intensity have necessitated the search for alternative means to control infectious disease. Enhancement of host immunity against infection has been permitted through the use of hematopoietic growth factors, which can shorten the duration of neutropenia and reduce the risk for bacterial and fungal infections. Hematopoietic growth factor-mobilized hematopoietic stem cells have also proven to be highly efficacious in permitting high-dose chemotherapy. Interferons, immunoregulatory cytokines, immune globulins, and immune lymphocytes also hold promise to enhance host immunity and reduce susceptibility for serious infectious morbidity. |
| | |
Authors:
|
J R Wingard; G J Elfenbein |
Related Documents
:
|
19997504 - Innate immune recognition of yersinia pseudotuberculosis type iii secretion. 19939494 - Aspergillus fumigatus conidial melanin modulates host cytokine response. 15329444 - Regulation by innate immune t lymphocytes in the host defense against pulmonary infecti... 20129784 - Cytosol as battleground: ubiquitin as a weapon for both host and pathogen. 22095544 - Evolution of immunity: no development without risk. 21120594 - Intracellular b7-h4 suppresses bile duct epithelial cell apoptosis in human primary bil... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Infectious disease clinics of North America Volume: 10 ISSN: 0891-5520 ISO Abbreviation: Infect. Dis. Clin. North Am. Publication Date: 1996 Jun |
Date Detail:
|
Created Date: 1997-01-13 Completed Date: 1997-01-13 Revised Date: 2006-04-24 |
Medline Journal Info:
|
Nlm Unique ID: 8804508 Medline TA: Infect Dis Clin North Am Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 345-64 Citation Subset: IM |
Affiliation:
|
Department of Medicine, University of Florida College of Medicine, Gainesville, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adjuvants, Immunologic
/
therapeutic use* Adoptive Transfer Antineoplastic Combined Chemotherapy Protocols / administration & dosage, adverse effects Bacterial Infections / prevention & control* Hematopoietic Cell Growth Factors / pharmacology* Hematopoietic Stem Cell Transplantation / methods Humans Immunization, Passive Interferons / therapeutic use Mycoses / prevention & control* Neutropenia / complications* |
| Chemical | |
Reg. No./Substance:
|
0/Adjuvants, Immunologic; 0/Hematopoietic Cell Growth Factors; 9008-11-1/Interferons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Granulocyte transfusions. Time for a second look.
Next Document: Recent progress and current problems in treatment of invasive fungal infections in neutropenic patie...