| Host genetic factors in susceptibility to HIV-1 infection and progression to AIDS. | |
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MedLine Citation:
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PMID: 20505255 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HIV-1 infection has rapidly spread worldwide and has become the leading cause of mortality in infectious diseases. The duration for development of AIDS (AIDS progression) is highly variable among HIV-1 infected individuals, ranging from 2-3 years to no signs of AIDS development in the entire lifetime. Several factors regulate the rate at which HIV-1 infection progresses to AIDS. Host genetic factors play an important role in the outcome of such complex or multifactor diseases as AIDS and are also known to regulate the rate of disease progression. This review focuses on the major host genes reported to affect the progression to AIDS in HIV-1 infected individuals. |
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Authors:
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Koushik Chatterjee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of genetics Volume: 89 ISSN: 0973-7731 ISO Abbreviation: J. Genet. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-27 Completed Date: 2010-10-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985113R Medline TA: J Genet Country: India |
Other Details:
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Languages: eng Pagination: 109-16 Citation Subset: IM |
Affiliation:
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Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, Republic of South Africa. koushik.chatterjee@uct.ac.za |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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genetics*,
immunology,
virology* Disease Progression* Genetic Predisposition to Disease / genetics* HIV-1 / immunology, physiology* Histocompatibility Antigens / genetics Humans Receptors, Cell Surface / genetics |
| Chemical | |
Reg. No./Substance:
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0/Histocompatibility Antigens; 0/Receptors, Cell Surface |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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