Document Detail


Host-environment medicine: a primary care model for the age of genomics.
MedLine Citation:
PMID:  12648255     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rapid developments in genomic and proteomic testing promise to impact the way in which clinicians assess disease risk and drug selection in their patients. Because most diseases result from host-environment interactions, however, primary care providers will need to avoid the trap of biological determinism by examining the important role of environmental factors in their clinical assessments and interventions. This article discusses the application of host-environment concepts to recent developments in the areas of genomics and proteomics.
Authors:
Peter M Rabinowitz; Alex Poljak
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of general internal medicine     Volume:  18     ISSN:  0884-8734     ISO Abbreviation:  J Gen Intern Med     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-21     Completed Date:  2003-08-29     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  8605834     Medline TA:  J Gen Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  222-7     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06510, USA. Peter.rabinowitz@yale.edu
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MeSH Terms
Descriptor/Qualifier:
Antidepressive Agents, Tricyclic / therapeutic use
Cytochrome P-450 CYP2D6 / genetics
Disease Susceptibility*
Environment*
Forecasting
Genomics*
Humans
Male
Middle Aged
Pain / drug therapy
Polymorphism, Genetic
Proteome*
Chemical
Reg. No./Substance:
0/Antidepressive Agents, Tricyclic; 0/Proteome; EC 1.14.14.1/Cytochrome P-450 CYP2D6
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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